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Overview
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Target Information
Target NameResistin; Adipose Tissue-Specific Secretory Factor; Adsf; C/Ebp-Epsilon-Regulated Myeloid-Specific Secreted Cysteine-Rich Protein; Cysteine-Rich Secreted Protein A12-Alpha-Like 2; Cysteine-Rich Secreted Protein Fizz3Database LinksRETN_HUMAN ; Reactome: R-HSA-6798695 ; Gene ID: 56729About TargetTissue Specificity: Expressed in white adipose tissue (at protein level). Widely expressed, with particularly strong expression in lung, bone marrow, breast and peripheral blood. Expressed strongly in bone marrow and at lower levels in lung, but not detected in other tissues. Isoform 2 is detected in adipose tissue, bone marrow, brain, lung, peripheral blood, placenta and thymus.
Function: Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes. Promotes chemotaxis in myeloid cells.
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Overview