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Overview
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This PAPPA2 CLIA Kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
Please contact us at for specific academic pricing.
Target Information
Target NamePappalysin-2; Pregnancy-Associated Plasma Protein A2; Papp-A2; Pregnancy-Associated Plasma Protein E1; Papp-EDatabase LinksPAPP2_HUMAN ; Reactome: R-HSA-381426 ; Gene ID: 60676About TargetTissue Specificity: Expressed abundantly in placenta, and non-pregnant mammary gland with low expression in the kidney, fetal brain and pancreas.
Function: Metalloproteinase which specifically cleaves insulin-like growth factor binding protein (IGFBP)-5 at the '163-Ser-|-Lys-164' bond. Shows limited proteolysis toward IGFBP-3.
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