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Target Information
Target NameOncostatin-M-Specific Receptor Subunit Beta; Interleukin-31 Receptor Subunit Beta; Il-31 Receptor Subunit Beta; Il-31r Subunit Beta; Il-31r-Beta; Il-31rbDatabase LinksOSMR_HUMAN ; Reactome: R-HSA-6788467 ; Gene ID: 9180About TargetTissue Specificity: Expressed in keratinocytes (at protein level). Expressed at relatively high levels in all neural cells as well as fibroblast and epithelial cells.
Function: Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events.
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