Name: Human Neuregulin 1-beta
Price: Inquiry

- Overview
  - Predicted MW: Monomer, 7.6 kDa (66 aa). Neuregulin 1-beta (NRG1-beta ) is one of many alternatively-spliced isoforms of the NRG1 gene and contains a soluble EGF-like domain. The EGF-like domain of NRG1-beta signals through the ErbB2, ErbB3, and ErbB4 receptor tyrosine kinases. NRG1-beta is an important growth factor involved in neuroinflammation, nerve regeneration, and cardiovascular processes.
    
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- Properties
  - Protein Name
    
    Pro-neuregulin-1, membrane-bound isoform, Pro-NRG1, Acetylcholine receptor-inducing activity, Breast cancer cell differentiation factor p45
    
    Source
    
    Genetically modified E.coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Reducing and Non-Reducing SDS PAGE at >= 95%
    
    Formulation
    
    Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
    Sterile water at 0.1 mg/mL
    
    Storage
    
    Store at -20°C
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    Q02297-6
    
    Gene ID
    
    3084
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.
- Applications
  - Application Description
    
    Centrifuge vial before opening, Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.

Human Neuregulin 1-beta

Human Neuregulin 1-beta

More Information

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