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Overview
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Target Information
Target NameMetallothionein-3; Mt-3; Gifb; Gif; Growth Inhibitory Factor; Metallothionein-Iii; Mt-IiiDatabase LinksMT3_HUMAN ; Reactome: R-HSA-5661231 ; Gene ID: 4504About TargetTissue Specificity: Abundant in a subset of astrocytes in the normal human brain, but greatly reduced in the Alzheimer disease (AD) brain.
Function: Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro.
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- Properties
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Overview