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Overview
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Human, Mouse IL-1alpha Recombinant Protein (Animal Free) Lyophilized from Innovative Research has been recombinantly produced in E. coli. This is a Lyophilized protein buffered in with a purity of ? 98% by SDS-PAGE gel and HPLC analyses.
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Background
IL-1? is a non-secreted, proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes, and other epithelial cells. Both IL-1? and IL-1? bind to the same receptor and have similar, if not identical, biological properties. These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, Bcell maturation and proliferation, mitogenic FGF-like activity and the release of prosTaglandin and collagenase from synovial cells. However, whereas IL-1? is a secreted cytokine, IL-1? is predominantly a cell-associated cytokine. Recombinant Human IL-1? is an 18.0 kDa protein containing 159 amino acid residues.
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- Properties
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Overview