Human, Mouse IL-13 Recombinant Protein (Animal Free) Lyophilized

Human, Mouse IL-13 Recombinant Protein (Animal Free) Lyophilized

Catalog Number:
P001418865INN
Mfr. No.:
IHUMSIL13RAFLY2UG
Price:
$613
  • Size:
    2UG
    Quantity:
    Add to Cart:
      • Overview
        • Human, Mouse IL-13 Recombinant Protein (Animal Free) Lyophilized from Innovative Research has been recombinantly produced in E. coli. This is a Lyophilized protein buffered in with a purity of ? 98% by SDS-PAGE gel and HPLC analyses.

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          Background

          IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1?, TNF-?, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching, resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 are cross-species reactive. Recombinant Human IL-13 is a 12.6 kDa protein consisting of 115 amino acid residues.

      • Properties
        • Protein Name
          IL13
          Source
          E. coli
          Type
          Animal Free Proteins
          Purification
          >98% by SDS-PAGE gel and HPLC analyses.
          Storage
          The recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing the recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

          * These products are supplied for manufacturing, research and laboratory use only.

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