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Overview
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Human, Mouse IFN-gamma Recombinant Protein (Animal Free) Lyophilized from Innovative Research has been recombinantly produced in E. coli. This is a Lyophilized protein buffered in with a purity of ? 98% by SDS-PAGE gel and HPLC analyses.
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Background
IFN-? is an acid-labile interferon produced by CD4 and CD8 T lymphocytes, as well as activated NK cells. IFN-? receptors are present in most immune cells, which respond to IFN-? signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-? signaling in antigen-presenting, cells and antigen-recognizing B and T lymphocytes, regulates the antigen-specific phases of the immune response. Additionally, IFN-? stimulates a number of lymphoid cell functions, including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-? is species-specific and is biologically active only in human and primate cells. Recombinant Murine IFN-? is a 15.6 kDa protein containing 134 amino acid residues.
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- Properties
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Overview