Human LDLR (Low Density Lipoprotein Receptor) ELISA Kit

Low-Density Lipoprotein Receptor; Ldl Receptor

LDLR_HUMAN ; Reactome: R-HSA-8856825 ; Gene ID: 3949

Function: Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. (Microbial infection) Acts as a receptor for hepatitis C virus in hepatocytes, but not through a direct interaction with viral proteins. (Microbial infection) Acts as a receptor for Vesicular stomatitis virus. (Microbial infection) In case of HIV-1 infection, may function as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.