Name: Human Interleukin-17A
Price: Inquiry

- Overview
  - Predicted MW: Dimer, 15.7/31.3 kDa (137/274 aa). Interleukin 17A (IL-17A), also known as CTLA-8, is a member of the IL-17 family of proteins. IL-17A is a proinflammatory cytokine that is secreted by activated CD4+ and CD8+ T lymphocytes. IL-17A acts through its receptor, IL-17R, to promote increased cytokine and chemokine secretion. In turn, the cytokines and chemokines mediate the immunoregulatory function of IL-17A by promoting the proliferation, maturation, and chemoattraction of neutrophils to inflammatory sites. Elevated levels of IL-17A are associated with rheumatoid arthritis, airway inflammation, allograft rejection, inflammatory bowel disease, psoriasis, cancer, and multiple sclerosis. Human, mouse, and rat IL-17A show activity on mouse cells.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    CTLA8, IL17, Cytotoxic T-lymphocyte-associated antigen 8
    
    Source
    
    Genetically modified E.coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Reducing and Non-Reducing SDS PAGE at >= 95%
    
    Formulation
    
    Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
    Sterile water at 0.1 mg/mL
    
    Storage
    
    Store at -20°C
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    More Information
    
    UniProt
    
    Q16552
    
    Gene ID
    
    3605
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Human Interleukin-17A

Human Interleukin-17A

More Information

We Also Recommend

Human Interleukin-17AF Heterodimer

Mouse Interleukin-17A

Rat Interleukin-17A