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Human Interferon-gamma

Human Interferon-gamma

Catalog Number:
P001413200ABE
Mfr. No.:
Abe32-12111
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      • Overview

        • Predicted MW: Monomer, 16.9 kDa (144 aa). Interferon gamma (IFN-gamma ) is a type II interferon that is critical during adaptive and innate immune responses to infection. IFN-gamma is produced by T cells and natural killer cells following antigen-specific activation. IFN-gamma binds IFN-gamma receptors (IFN-gamma R1 and IFN-gamma R2), which are expressed on most immune cells, to activate the JAK-STAT pathway. IFN-gamma -induced signaling increases the expression of class 1 major histocompatibility complex (MHC) molecules. Human IFN-gamma is not cross-reactive with mouse IFN-gamma .

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      • Properties
        • Protein Name
          Type II interferon, T cell interferon, Immune Interferon, MAF
          Source
          Genetically modified E.coli
          Type
          Recombinant Proteins
          Purification
          Reducing and Non-Reducing SDS PAGE at >= 95%
          Formulation
          Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5
          Sterile water at 0.1 mg/mL
          Storage
          Store at -20°C
          Endotoxin
          Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.

          More Information

          UniProt
          P01579
          Gene ID
          3458

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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