Name: Human IGF-Binding Protein 7 Recombinant Protein (Animal Free) Lyophilized
Price: 613.00 USD

- Overview
  - Human IGF-Binding Protein 7 Recombinant Protein (Animal Free) Lyophilized from Innovative Research has been recombinantly produced in E. coli. This is a Lyophilized protein buffered in with a purity of ? 98% by SDS-PAGE gel and HPLC analyses.
    
    Please contact us at for specific academic pricing.
    
    Background
    
    IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently, there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP7 is expressed in a wide range of normal human tissues, and it generally shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin. It plays a role in skeletal myogenesis by binding to IGF in a manner that inhibits IGF-induced differentiation of skeletal myoblasts, without affecting IGF-induced proliferation. Additionally, IGF-BP7 suppresses growth and colony formation of prostate and breast cancer cell lines through an IGF-independent mechanism, which causes a delay in the G1 phase of the cell cycle and increased apoptosis. Recombinant Human IGF-BP7 is a 26.4 kDa protein consisting of 256 amino acid residues.
- Properties
  - Protein Name
    
    IGFBP7
    
    Source
    
    E. coli
    
    Type
    
    Animal Free Proteins
    
    Purification
    
    >98% by SDS-PAGE gel and HPLC analyses.
    
    Storage
    
    The recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing the recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
    
    * These products are supplied for manufacturing, research and laboratory use only.

Human IGF-Binding Protein 7 Recombinant Protein (Animal Free) Lyophilized

Human IGF-Binding Protein 7 Recombinant Protein (Animal Free) Lyophilized

Background

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