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Overview
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This HYOU1 CLIA Kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
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Target Information
Target NameHypoxia Up-Regulated Protein 1; 150 Kda Oxygen-Regulated Protein; Orp-150; 170 Kda Glucose-Regulated Protein; Grp-170Database LinksHYOU1_HUMAN ; Reactome: R-HSA-3000484 ; Gene ID: 10525About TargetTissue Specificity: Highly expressed in tissues that contain well-developed endoplasmic reticulum and synthesize large amounts of secretory proteins. Highly expressed in liver and pancreas and lower expression in brain and kidney. Also expressed in macrophages within aortic atherosclerotic plaques, and in breast cancers.
Function: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding.
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