Human FLNC (Filamin C, Gamma) ELISA Kit

Filamin-C; Fln-C; Flnc; Abp-280-Like Protein; Abp-L; Actin-Binding-Like Protein; Filamin-2; Gamma-Filamin

Uniprot ID: VILI_HUMAN ; Reactome: R-HSA-446353 ; Gene ID: 2318

Tissue Specificity: Highly expressed in striated muscles. Weakly expressed in thyroid, fetal brain, fetal lung, retina, spinal cord and bone marrow. Not expressed in testis, pancreas, adrenal gland, placenta, liver and kidney.

Function: Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross-linking protein. May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z lines in muscle cells. Critical for normal myogenesis and for maintaining the structural integrity of the muscle fibers.