Human Fibroblast Growth Factor-6

Human Fibroblast Growth Factor-6

Catalog Number:
P001412036ABE
Mfr. No.:
Abe32-12048
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      • Overview
        • Predicted MW: Monomer, 18.9 kDa (169 aa). Fibroblast growth factor 6 (FGF-6) is a heparin-binding growth factor that is expressed in epithelial and mesenchymal lineages. FGF-6 binds and signals through the FGF receptors FGFR1, FGFR2, and FGFR4. FGF-6 functions as a mitogen for vascular endothelial cells and fibroblasts. FGF-6 is also an important factor driving muscle differentiation and regeneration.

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      • Properties
        • Protein Name
          Heparin secretory-transforming protein 2, HST-2, HSTF-2, Heparin-binding growth factor 6, HBGF-6
          Source
          Genetically modified E.coli
          Type
          Recombinant Proteins
          Purification
          Reducing and Non-Reducing SDS PAGE at >= 95%
          Formulation
          Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate and 50 mM sodium chloride, pH 7.5
          Sterile water at 0.1 mg/mL
          Storage
          Store at -20°C
          Endotoxin
          Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
          Activity
          Biological Activity was determined by 3T3 Proliferation w 1 ug heparin <=1 ng/mL; >= 1.0 x 10^6 units/mg. Centrifuge vial before opening, Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C and avoid repeat freeze thaws. Upon reconstitution, a small amount of visible precipitate can be expected. A 10% overfill has been added to the total material vialed to compensate for this loss.

          More Information

          UniProt
          Gene ID
          2251

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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