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Target Information
Target NameErythropoietin; EpoetinDatabase LinksUniprot ID: TGM3L_HUMAN ; Reactome: R-HSA-1234158 ; Gene ID: 2056About TargetTissue Specificity: Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.
Function: Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.
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