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Overview
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Predicted MW: Monomer, 8.4 kDa (74 aa). Eotaxin, also known as Eotaxin-1 and CCL11, is a chemokine that recruits eosinophils to sites of allergic inflammation. Eotaxin signals through the G protein-coupled chemokine receptors CCR2, CCR3, and CCR5. Eotaxin also negatively regulates adult neurogenesis, and high Eotaxin levels are associated with impaired learning and memory.
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Overview