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Overview
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Target Information
Target NameD-Amino-Acid Oxidase; Daao; Damox; DaoDatabase LinksUniprot ID: RET1_HUMAN ; Reactome: R-HSA-389661 ; Gene ID: 1610About TargetFunction: Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.
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Overview