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Target Information
Target NameClaudin-4; Clostridium Perfringens Enterotoxin Receptor; Cpe-R; Cpe-Receptor; Williams-Beuren Syndrome Chromosomal Region 8 ProteinDatabase LinksUniprot ID: PDE4D_HUMAN ; Reactome: R-HSA-420029 ; Gene ID: 1364About TargetFunction: Channel-forming tight junction protein that mediates paracellular chloride transport in the kidney. Plays a critical role in the paracellular reabsorption of filtered chloride in the kidney collecting ducts. Claudins play a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
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