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Overview
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This AIF1 CLIA Kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
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Target Information
Target NameAllograft Inflammatory Factor 1; Aif-1; Ionized Calcium-Binding Adapter Molecule 1; Protein G1Database LinksUniprot ID: DSG1_HUMAN ; Gene ID: 199About TargetTissue Specificity: Detected in T-lymphocytes and peripheral blood mononuclear cells.
Function: Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
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