HTR2B Polyclonal Antibody

HTR2B Polyclonal Antibody

Catalog Number:
A001513978RED
Mfr. No.:
RD89510A
Price:
$416
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      • Overview
        • Calculated MW: 29kDa/34kDa
          Observed MW: 29kDa

          Please contact us at for specific academic pricing.

          Background

          This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Recombinant fusion protein of human HTR2B
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide,50% glycerol,pH7.3.
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1mg/mL
          Antigen
          HTR2B, 5-HT(2B), 5-HT-2B, 5-HT2B (Gene ID:3357; UniProt:P41595)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:200-1:1000

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