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Overview
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Calculated MW: 43kDa
Observed MW: 38kDaPlease contact us at for specific academic pricing.
Background
G-protein coupled receptor for 5-hydroxytryptamine (serotonin. Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
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