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HSPA5 Polyclonal Antibody (1 mg/mL) for WB

HSPA5 Polyclonal Antibody (1 mg/mL) for WB

Catalog Number:
A001514675RED
Mfr. No.:
RD90660A
Price:
$326
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      • Overview

        • Calculated MW: 25 kDa
          Observed MW: 27 kDa

          Please contact us at for specific academic pricing.

          Background

          Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen.Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate .Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR).In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to disrupt the dimerization of ERN1/IRE1, thereby inactivating ERN1/IRE1.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          mouse
          Immunogen
          Recombinant Human HSPA5 protein expressed by E.coli
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH 7.4
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1 mg/mL
          Antigen
          HSPA5, GRP78, 78 kDa glucose-regulated protein, Binding-immunoglobulin protein, Heat shock protein 70 family protein 5, Heat shock protein family A member 5 , Immunoglobulin heavy chain-binding protein (UniProt:P11021)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:1000

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