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Overview
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Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix. Heparanase (HPSE) is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. HPSE is critical regulator of angiogenesis and tumor metastasis.
This lentivirus expresses human HPSE shRNA under the control of the U6 promoter..Please contact us at for specific academic pricing.
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