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Overview
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HPR Human Recombinant produced in E. Coli is a single,non-glycosylated polypeptide chain containing 352 amino acids (20-348 a.a) andhaving a molecular mass of 39.3kDa. HPR is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Haptoglobin-RelatedProtein also known as HPR, is a primate-specific plasma protein related withapolipoprotein L-I (apoL-I)-containing high-density lipoprotein (HDL) particleswhich shown to be a part of the innate immune defense. HPR-bound hemoglobin mightcontribute to the biologic activity of the circulating apoL-I/Hprcontaining HDLparticles. HPR is a clinically significant forecaster of recurrence of breastcancer.
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Overview