Name: HMGA2 Recombinant Protein
Price: Inquiry

- Overview
  - HMGA2 Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 117 amino acids (1-109 a.a) and having a molecular mass of 12.8kDa. HMGA2 is fused to an 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques. High Mobility Group AT-Hook 2 (HMGA2) is a memberof the non-histone chromosomal high mobility group (HMG) family. HMG proteins performas architectural factors and are necessary components of the enhancesome. This protein containsstructural DNA-binding domains and may function as a transcriptional regulatingfactor. In addition, identification of the deletion, amplification, and rearrangement of thisgene that are associated with myxoid liposarcoma proposes a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is implicatedin diet-induced obesity. Amongthe Diseases associated with HMGA2 are diffuse lipomatosis, and 12q14microdeletion syndrome.
    
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- Properties
  - Protein Name
    
    High Mobility Group AT-Hook 2, HMGIC, High-Mobility Group(Nonhistone Chromosomal) Protein Isoform I-C, High Mobility Group AT-HookProtein, BABL, HMGI-C, LIPO, STQTL9, High Mobility Group Protein HMGI-C, HMGA2.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 80.0% as determined by SDS-PAGE.
    
    Formulation
    
    HMGA2 protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 50% glycerol, 2mM DTT and 250mM Imidazole.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

HMGA2 Recombinant Protein

HMGA2 Recombinant Protein

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