HLA-F Polyclonal Antibody

HLA-F Polyclonal Antibody

Catalog Number:
A001508907RED
Mfr. No.:
RD265765A
Price:
$347
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      • Overview
        • Calculated MW: 28 kDa/39 kDa/50 kDa
          Observed MW: 50 kDa

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          Background

          This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain.

      • Properties
        • Host
          rabbit
          Isotype
          IgG
          Reactivity
          human; rat
          Immunogen
          Recombinant fusion protein of human HLA-F (NP_001091949.1).
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.02% sodium azide, 50% glycerol, pH7.3
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          1 mg/mL
          Antigen
          HLA-F, CDA12, HLA-5.4, HLA-CDA12, HLAF (Gene ID:3134; UniProt:P30511)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:2000

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