HLA-E Polyclonal Antibody (0.9 mg/mL) for IHC, ELISA

HLA-E Polyclonal Antibody (0.9 mg/mL) for IHC, ELISA

Catalog Number:
A001507003RED
Mfr. No.:
RD218997A
Price:
$253
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      • Overview
        • Gene Accession: BC002578

          Please contact us at for specific academic pricing.

          Background

          HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Fusion protein of human HLA-E
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          0.9 mg/mL
          Antigen
          HLA class I histocompatibility antigen E alpha chain, EA1.2, EA2.1, HLA 6.2, HLA class I histocompatibility antigen alpha chain E, HLA class I histocompatibility antigen E alpha chain precursor , HLA class I histocompatibility antigen E alpha chain precursor, HLA6.2, HLAE, Lymphocyte antigen, Major histocompatibility complex class I E, MHC, MHC class I antigen E, MHC HLA E alpha 1, MHC HLA E alpha 2.1, QA1 (UniProt:P13747)

          * For reference only.

      • Applications
        • Application
          IHC; ELISA
        • Application Dilutions
          IHC 1:50-1:300
          ELISA 1:5000-1:10000

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