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Overview
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Background
Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fibers. Two molecules of each of the four core histones (H2A, H2B, H3 and H4) form the octamer, which is comprised of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Human and mouse Histone H4 are subject to trimethylation at Lys 20, a modification that may be necessary for select DNA transactions or chromatin state transitions.
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- Properties
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Overview
Histone H4 (tri methyl K20) Rabbit mAb
Histone H4 (tri methyl K20) Rabbit mAb
Catalog Number:
A001547883RED
Mfr. No.:
RDSA63017
Price:
$483
Size:
100μL
Quantity:
Add to Cart:
.