High Sensitivity Estradiol (Serum & Plasma) ELISA Kit

Estradiol (C18H24O2), also known as E2, is a major female sex hormone (strongest estrogen) which regulates menstrual reproductive cycles as well as the estrous cycle. It is a key regulator of growth, differentiation, and function in a wide array of tissues, including the male and female reproductive tracts, mammary gland, brain, skeletal and cardiovascular systems. E2 has two distinct intracellular receptors; ERα and ERβ which are mediating the main biological functions of E2. ERα and ERβ are encoded by unique genes possessing the functional domain characteristics of the steroid/thyroid hormone superfamily of nuclear receptors. ERα, as the predominant form, is expressed in the breast, uterus, cervix, and vagina., whereas ERβ exhibits a more limited pattern and is primarily expressed in the ovary, prostate, testis, spleen, lung, hypothalamus, and thymus.

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