α-helical CRF (9-41)

α-helical CRF (9-41)

Catalog Number:
P004516755LIF
Mfr. No.:
PEPTIDE-CR-010
Price:
$378
  • Size:
    1mg
    Quantity:
    Add to Cart:
      • Overview
        • CRF antagonist.
          α-helical CRF (9-41) is a corticotropin releasing factor receptor (CRF) antagonist with Ki values of 17, 5 and 0.97 nM at human CRF1, rat CRF2 and mouse CRF2 receptors respectively. α-helical CRF (9-41) decreases anxiety-like behaviour in the conditioned fear test and reverses the potentiation of startle amplitude produced by administration of CRF in anxiety models. α-helical CRF (9-41) pre-treatment blocks CRF induced food intake inhibition.

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      • Properties
        • Categories
          Peptides
          Alternative Name
          α-helical-Corticotropin-Releasing Factor 9-41, AHCRF
          Molecular Formula
          C166H274N46O53S2
          Molecular Weight
          3827
          Appearance
          Freeze dried solid
          Purity
          >95% by HPLC
          Solubility
          Soluble to 1 mg/ml in 0.1% TFA
          Other Properties
          Sequence: H-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Met-Leu-Glu-Met-Ala-Lys-Ala-Glu-Gln-Glu-Ala-Glu-Gln-Ala-Ala-Leu-Asn-Arg-Leu-Leu-Leu-Glu-Glu-Ala-NH2,DLTFHLLREMLEMAKAEQEAEQAALNRLLLEEA-NH2
          Modification: C-terminal amide
          Storage
          Store dry, frozen and in the dark

          * Please note: this product can only be supplied to registered research and development facilities, and may be used for in vitro research use only, not for administration to humans or animals.

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