HBG1/HBG2 Polyclonal Antibody (0.6 mg/mL) for WB, IHC, ELISA

HBG1/HBG2 Polyclonal Antibody (0.6 mg/mL) for WB, IHC, ELISA

Catalog Number:
A001506806RED
Mfr. No.:
RD218774A
Price:
$253
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      • Overview
        • Calculated MW: 16 kDa
          Observed MW: Refer to figures
          Gene Accession: BC010914

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          Background

          The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          Fusion protein of human HBG1/HBG2
          Purification
          Antigen affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
          Storage
          Store at -20°C. Avoid freeze-thaw cycles.
          Concentration
          0.6 mg/mL
          Antigen
          A gamma globin, G gamma globin, Gamma 1 globin, Gamma 2 globin, Gamma A hemoglobin, Gamma globin, Hb F Agamma, Hb F Ggamma, hbfagamma, hbfggamma, HBG 1, HBG 2, HBG1, HBG2, HBGA, HBGR, Hemoglobin gamma 1 chain , Hemoglobin gamma 2 chain , Hemoglobin gamma A, Hemoglobin gamma A chain , Hemoglobin gamma G, Hemoglobin gamma G chain , Hemoglobin gamma regulator of, Hemoglobin subunit gamma 1, Hemoglobin subunit gamma 2, HSGGL 1, HSGGL1, Methemoglobin, PRO 2979, PRO2979 (UniProt:P69891,P69892)

          * For reference only.

      • Applications
        • Application
          WB; IHC; ELISA
        • Application Dilutions
          WB 1:500-1:2000
          IHC 1:40-1:200
          ELISA 1:5000-1:10000

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