GST-A20(1-365)

GST-A20(1-365)

Catalog Number:
DE01097456UBP
Mfr. No.:
H3211
Price:
$387
  • Size:
    100 µg
    Quantity:
    Add to Cart:
      • Overview
        • Deubiquitinating enzymes (DUBs) are proteases that posses the ability to cleave ubiquitin chains or the isopeptide bond that conjugates ubiquitin with a substrate. Human cells have approximately 100 DUBs that play important roles in regulating various cellular events. A20 downregulates the NF-κB pathway and proinflammatory gene expression in cells such as macrophages. The N-terminal domain of A20 contains the DUB activity.

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      • Properties
        • Protein Name
          TNFAIP3; OTUD7C; TNFA1P2
          Source
          Bacterial recombinant
          Formulation
          20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
          Storage
          Store at -80°C; avoid multiple freeze-thaw cycles
          Concentration
          See tube label
          Molecular Weight
          42.9 kDa without GST tag
          Sequence
          NCBI RefSeq: NM_006290

          * Research Use Only

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