GRIN2C Polyclonal Antibody

GRIN2C Polyclonal Antibody

Catalog Number:
A001512718RED
Mfr. No.:
RD87808A
Price:
$416
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      • Overview
        • Calculated MW: 114kDa/121kDa/124kDa/126kDa/128kDa
          Observed MW: 140kDa

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          Background

          This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of ionotropic glutamate receptor. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          mouse
          Immunogen
          Recombinant fusion protein of human GRIN2C
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.01% thiomersal,50% glycerol,pH7.3.
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1mg/mL
          Antigen
          GRIN2C, GluN2C, NMDAR2C, NR2C, NMDA 2C (Gene ID:2905; UniProt:Q14957)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:1000

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