Granzyme B Rabbit mAb

Granzyme B Rabbit mAb

Catalog Number:
A001548813RED
Mfr. No.:
RDSA65389
Price:
$470
  • Size:
    100μL
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

      • Properties
        • Host
          rabbit
          Antibody Type
          monoclonal
          Isotype
          IgG
          Reactivity
          human
          Immunogen
          A synthesized peptide derived from human Granzyme B
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Storage
          Store at -20°C. Avoid freeze / thaw cycles.
          Molecular Weight
          38kDa (Calculated)
          Antigen
          Granzyme B;Cathepsin G-like 1;CTSGL1;Lymphocyte protease;Fragmentin-2;Granzyme-2;Human lymphocyte protein;SECT;GZMB;CGL1;CSPB;CTLA1;GRB (UniProt:P10144)

          * This product is for Research Use Only.

      • Applications
        • Application
          IHC; ICC/IF; IP
        • Application Dilutions
          IHC 1:50-1:200
          ICC/IF 1:50-1:200
          IP 1:50

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