Granzyme B Mouse Monoclonal Antibody

Granzyme B Mouse Monoclonal Antibody

Catalog Number:
A001450554ZEN
Mfr. No.:
Zen-222306
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      • Overview
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          Background

          This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. [provided by RefSeq, Sep 2016]

      • Properties
        • Host
          mouse
          Isotype
          Mouse IgG2a
          Reactivity
          human
          Immunogen
          Purified recombinant fragment of human GZMB expressed in E. Coli.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Purified antibody in PBS with 0.05% sodium azide
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Antigen
          (Gene ID:3002; UniProt:P10144)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          IHC-P; ELISA
        • Application Dilutions
          IHC 1/100-1/200
          ELISA 1/10000

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