Granzyme B Monoclonal Antibody

Granzyme B Monoclonal Antibody

Catalog Number:
A001510621RED
Mfr. No.:
RD5024R
Price:
$381
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      • Overview
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          Background

          Granzyme B is a serine protease, which mediates the apoptosis signaling pathway of cytotoxic T lymphocytes (CTL) and natural killer cells (NK). Granzyme B is synthesized in the form of inactive protease, stored in lysosomal granules and released during the degradation of effector cells. The results shows that granzyme B is expressed in peripheral T-cell lymphoma (PTCL) and NK cell lymphoma by immunohistochemistry. The expression of cytotoxic proteins may play an important role in the differentiation and classification of peripheral T-cell and NK cell lymphoma, such as granzyme B, because many tumors of this type do not have specific morphology and phenotype.

      • Properties
        • Host
          rabbit
          Antibody Type
          monoclonal
          Reactivity
          human
          Formulation
          TBS with 0.1% Proclin300, PH7.4
          Concentration
          100μg/mL for the RTU antibody, 1mg/mL for the concentrated antibody
          Antigen
          (UniProt:P10144)

          * For reference only.

      • Applications
        • Application
          IHC-P

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