GluR2 (phospho-Ser880) antibody

GluR2 (phospho-Ser880) antibody

Catalog Number:
A001551634RED
Mfr. No.:
RDSA62270
Price:
$483
  • Size:
    100μL
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse; rat
          Immunogen
          Peptide sequence around phosphorylation site of serine 880 (I-E-S(p)-V-K) derived from Human Glutamate receptor 2.
          Purification
          Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
          Conjugate
          Unconjugated
          Formulation
          Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
          Storage
          Store at -20°C. Avoid freeze / thaw cycles.
          Concentration
          1.0 mg/mL
          Molecular Weight
          100kDa (Observed)
          Antigen
          GRIA2;GluR-2;GluR-B;GluR-K2;AMPA 2 (Gene ID:2891; UniProt:P42262)

          * This product is for Research Use Only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:500-1:1000

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