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Overview
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GLTP Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 232 amino acids (1-209 a.a.) and having a molecular mass of 26.2kDa. GLTP is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Glycolipid transfer protein (GLTP) accelerates the intermembrane transfer of different glycolipids. GLTP catalyzes the transfer of various glycosphingolipids between membranes however does not catalyze the transfer of phospholipids. GLTP is involved in the intracellular translocation of glucosylceramides. The GLTP protein is similar to bovine and porcine proteins which accelerate transfer of certain glycosphingolipids and glyceroglycolipids between membranes. GLTP is assumed to be a cytoplasmic protein. GLTP is detected in fibroblasts and in various cancer cell lines.
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Overview