GLRB Mouse Monoclonal Antibody

GLRB Mouse Monoclonal Antibody

Catalog Number:
A001450576ZEN
Mfr. No.:
Zen-222896
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      • Overview
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          Background

          This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.

      • Properties
        • Host
          mouse
          Isotype
          Mouse IgG2b
          Reactivity
          human
          Immunogen
          Purified recombinant fragment of human GLRB expressed in E. Coli.
          Purification
          Affinity Purified
          Conjugate
          Unconjugated
          Formulation
          Purified antibody in PBS with 0.05% sodium azide
          Storage
          Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
          Antigen
          (Gene ID:2743; UniProt:P48167)

          * Research Use Only Product (RUO). Not for Diagnosis or Therapeutic Use.

      • Applications
        • Application
          ICC/IF; FC; ELISA
        • Application Dilutions
          IF 1/50-1/200
          FC 1/50-1/100
          ELISA 1/10000

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