Glibenclamide

Glibenclamide

Catalog Number:
FC01365242APE
Mfr. No.:
APE-B1296
Price:
$180
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      • Overview
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          Background

          Glibenclamide is a sulfonylurea compound that modulates insulin production. Sulfonylureas bind to ATP-dependent K+ channels in beta cells of the pancreas, depolarizing them and stimulating the release of Ca2+, which in turn stimulates insulin production.

      • Properties
        • Categories
          Insulin production modulator
          Alternative Name
          5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
          CAS Number
          10238-21-8
          Molecular Formula
          C23H28ClN3O5S
          Molecular Weight
          494
          Appearance
          A solid
          Purity
          98.53%
          Solubility
          ≥49.4 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
          Storage
          Store at -20°C
          SMILES
          COC1=C(C=C(C=C1)Cl)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3

          * For Research Use Only

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