Glial Fibrillary Acidic Protein ELISA (GFAP ELISA)

Glial Fibrillary Acidic Protein (GFAP) is the principal 8-9 nm intermediate filament in mature astrocytes of the Central Nervous System (CNS). The findings showed that GFAP is released after traumatic brain injury severity and outcome into the blood very soon after traumatic brain injury (TBI), and that GFAP is not released after multiple trauma without brain injury. In the CNS following injury, either as a result of trauma, disease, genetic disorders, or chemical insult, astrocytes become reactive and respond in astrogliosis. Astrogliosis is characterized by rapid synthesis of GFAP. GFAP normally increases with age and there is a wide variation in the collection and processing of human brain tissue. GFAP is also an established biomarker of retinal stress.
The Glial Fibrillary Acidic Protein ELISA (GFAP ELISA) is for Research Use Only. The Glial Fibrillary Acidic Protein ELISA (GFAP ELISA) is not for use in diagnostic procedures.

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