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Overview
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Calculated MW: 4 kDa/12 kDa/15 kDa/18 kDa/19 kDa/21 kDa/24 kDa
Observed MW: 20 kDaPlease contact us at for specific academic pricing.
Background
Growth/differentiation factor 8(Mstn,GDF-8) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. It is expressed specifically in developing and adult skeletal muscle. It exists as a homodimer,and interacts with WFIKKN2,leading to inhibit its activity. This protein can act specifically as a negative regulator of skeletal muscle growth. It regulates cell growth and differentiation in both embryonic and adult tissues.
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