Name: FSBP Recombinant Protein
Price: Inquiry

- Overview
  - FSBP Human Recombinant produced in E. Coli is a single, non-glycosylated polypeptide chain containing 322 amino acids (1-299 a.a.) and having a molecular mass of 37.2kDa. FSBP is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Fibrinogen silencer-binding protein (FSBP), interacts with X11alpha. The X11alpha/FSBP complex send signals to the nucleus in order to repress glycogen synthase kinase-3beta promoter activity. X11alpha is a neuronal adaptor protein that interacts with the amyloid precursor protein (APP) via a centrally located phosphotyrosine binding domain to inhibit the production of Abeta peptide that is deposited in Alzheimer's diseased brains.
    
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- Properties
  - Protein Name
    
    Fibrinogen silencer-binding protein, FSBP.
    
    Source
    
    E. coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 85.0% as determined by SDS-PAGE.
    
    Formulation
    
    FSBP protein solution (0.25mg/ml) contains 20mM Tris-HCl buffer, (pH 8.0), 1M Urea and 10% glycerol.
    
    Storage
    
    Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

FSBP Recombinant Protein

FSBP Recombinant Protein

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