Name: Flavin adenine dinucleotide
Price: 180.00 USD

- Overview
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    Background
    
    Flavin adenine dinucleotide is used as a redox cofactor by a variety of proteins involved in several important enzymatic reactions in metabolism. In human, most flavoproteins contain one or more loosely bound flavin adenine dinucleotide moieties. Flavoproteins include the succinate dehydrogenase complex, α-ketoglutarate dehydrogenase, folate/FAD-dependent tRNA methyltransferases, N-hydroxylating flavoprotein monooxygenases, and apoptosis-inducing factor 2. Flavoproteins are predominately located in the mitochondria due to their redox power. Of all flavoproteins, more than 90% perform redox reactions and ~ 10% are lyases, transferases, isomerases and ligases involved in nonredox reactions.
    
    1. Kohlmeier M. Chapter 10 - Water-Soluble Vitamins and Nonnutrients. Nutrient Metabolism (Second Edition), 2015, 567-671.
    2. Lienhart WD, Gudipati V, Macheroux P. The human flavoproteome. Archives of Biochemistry and Biophysics, 2013, 535(2): 150-162.
    3. Macheroux P, Kappes B, Ealick SE. Flavogenomics--a genomic and structural view of flavin-dependent proteins. The FEBS Journal, 2011, 278(15): 2625-2634.
    4. Sugiyama S, Ozawa T. Protection of chlorpromazine-induced arrhythmia by flavin-adenine-dinucleotide in canine heart. Japanese Heart Journal, 1979, 20(5): 657-665.
- Properties
  - Categories
    
    A redox cofactor (electron carrier), involved in several important enzymatic reactions in metabolism
    
    CAS Number
    
    146-14-5
    
    Molecular Formula
    
    C27H33P2N9O15
    
    Molecular Weight
    
    785.55
    
    Appearance
    
    A solid
    
    Purity
    
    98.00%
    
    Solubility
    
    insoluble in EtOH; insoluble in DMSO; ≥196.5 mg/mL in H2O
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    CC1=CC(N=C(C(O)=N2)C3=NC2=O)=C(N3C[[email protected]@](O)([H])[[email protected]@](O)([H])[[email protected]@](O)([H])COP(O)(OP(O)(OC[[email protected]](O4)([H])[[email protected]](O)([H])[[email protected]](O)([H])[[email protected]]4([H])N5C=NC(C5=NC=N6)=C6N)=O)=O)C=C1C
    
    * For Research Use Only