FIG4 Polyclonal Antibody

FIG4 Polyclonal Antibody

Catalog Number:
A001513057RED
Mfr. No.:
RD88182A
Price:
$416
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      • Overview
        • Calculated MW: 135kDa
          Observed MW: 135kDa

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          Background

          The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J.

      • Properties
        • Host
          rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          human; mouse
          Immunogen
          Recombinant fusion protein of human FIG4
          Purification
          Affinity purification
          Conjugate
          Unconjugated
          Formulation
          PBS with 0.01% thiomersal,50% glycerol,pH7.3.
          Storage
          Store at -20°C Valid for 12 months. Avoid freeze-thaw cycles.
          Concentration
          1mg/mL
          Antigen
          FIG4, ALS11, BTOP, CMT4J, KIAA0274, SAC3, YVS, dJ249I4.1 (Gene ID:9896; UniProt:Q92562)

          * For reference only.

      • Applications
        • Application
          WB
        • Application Dilutions
          WB 1:200-1:2000

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