FHL3 Recombinant Protein

FHL3 Recombinant Protein

Catalog Number:
P001415235ABE
Mfr. No.:
Abe32-3832
Price:
  • Size:
    10 µg
    Quantity:
    Add to Cart:
      • Overview
        • FHL3 Human Recombinant produced in E. Coli is a single,non-glycosylated polypeptide chain containing 303 amino acids (1-280 a.a) andhaving a molecular mass of 33.6kDa. FHL3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Fourand a half LIM domains 3 (FHL3) belongs to a family of proteins containing afour-and-a-half LIM domain, which is a highly conserved double zinc fingermotif. FHL3 has been shown to interact with the cancer developmental regulatorsSMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and thehigh-affinity IgE beta chain regulator MZF-1. FHL3 is involved in tumorsuppression, repression of MyoD expression, and repression of IgE receptorexpression. Two transcript variants encoding different isoforms have been foundfor this gene.

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      • Properties
        • Protein Name
          Four And A Half LIM Domains 3, SLIM2, Skeletal MuscleLIM-Protein 2, FHL-3, SLIM-2, Four And A Half LIM Domains Protein 3, LIM-OnlyProtein FHL3.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greaterthan 90.0% as determined by SDS-PAGE.
          Formulation
          FHL3 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
          Storage
          Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please avoid freeze thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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