Fetuin-A ELISA

The Fetuin-A ELISA is an enzyme immunoassay for the quantitative determination of human Fetuin-A, also known as alpha-2-HS glycoprotein (AHSG), in serum. Fetuin-A, also known as alpha-2-HS glycoprotein, is a 59 kDa glycoprotein that consists of two amino-terminal cystatin domains and a smaller carboxyl-terminal domain. Fetuin-A is synthesized by the liver and secreted into blood stream, where its concentration in adult mammals ranges from 0.5 – 1.5 g/L. Fetuin-A occurs in high serum concentration during fetal life and involves in protease inhibitory activities and development associated regulation of calcium metabolism and osteogenesis. It accumulates in bones and teeth as a major fraction of noncollagenous bone proteins. Studies have demonstrated that Fetuin-A is the major calcification inhibitor found in serum, where it interferes with calcium salt precipitation.
The Fetuin-A ELISA is for Research Use Only. Not for use in diagnostic procedures.

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