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Overview
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Calculated MW: 43kDa/51kDa/52kDa
Observed MW: 51kDaPlease contact us at for specific academic pricing.
Background
Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. Activates both RAS/MAPK and PI3K/AKT/TOR signaling cascades downstream of EGFR. Required for the RAS/MAPK signaling cascade activation upon EGFR stimulation, it also activates both signaling cascades independently of EGFR activation.
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