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Overview
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Calculated MW: 26 kDa
Observed MW: Refer to figures
Gene Accession: NP115709Please contact us at for specific academic pricing.
Background
Involved in redox regulation of the cell.Acts as an antioxidant. Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation. May affect bone resorption and help to maintain bone mass. Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway.
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